Pesquisa | Secretaria de Estado da Saúde

1.

Mpox infection protects against re-challenge in rhesus macaques.

Aid, Malika; Sciacca, Michaela; McMahan, Katherine; Hope, David; Liu, Jinyan; Jacob-Dolan, Catherine; Powers, Olivia; Barrett, Julia; Wu, Cindy; Mutoni, Audrey; Murdza, Tetyana; Richter, Hannah; Velasco, Jason; Teow, Elyse; Boursiquot, Mona; Cook, Anthony; Orekov, Tatyana; Hamilton, Melissa; Pessaint, Laurent; Ryan, Alaina; Hayes, Tammy; Martinot, Amanda J; Seaman, Michael S; Lewis, Mark G; Andersen, Hanne; Barouch, Dan H.

Cell ; 186(21): 4652-4661.e13, 2023 10 12.

Artigo Inglês | MEDLINE | ID: mdl-37734373

2.

Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.

Tong, Pei; Gautam, Avneesh; Windsor, Ian W; Travers, Meghan; Chen, Yuezhou; Garcia, Nicholas; Whiteman, Noah B; McKay, Lindsay G A; Storm, Nadia; Malsick, Lauren E; Honko, Anna N; Lelis, Felipe J N; Habibi, Shaghayegh; Jenni, Simon; Cai, Yongfei; Rennick, Linda J; Duprex, W Paul; McCarthy, Kevin R; Lavine, Christy L; Zuo, Teng; Lin, Junrui; Zuiani, Adam; Feldman, Jared; MacDonald, Elizabeth A; Hauser, Blake M; Griffths, Anthony; Seaman, Michael S; Schmidt, Aaron G; Chen, Bing; Neuberg, Donna; Bajic, Goran; Harrison, Stephen C; Wesemann, Duane R.

Cell ; 184(19): 4969-4980.e15, 2021 09 16.

Artigo Inglês | MEDLINE | ID: mdl-34332650

3.

B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.

Scheid, Johannes F; Barnes, Christopher O; Eraslan, Basak; Hudak, Andrew; Keeffe, Jennifer R; Cosimi, Lisa A; Brown, Eric M; Muecksch, Frauke; Weisblum, Yiska; Zhang, Shuting; Delorey, Toni; Woolley, Ann E; Ghantous, Fadi; Park, Sung-Moo; Phillips, Devan; Tusi, Betsabeh; Huey-Tubman, Kathryn E; Cohen, Alexander A; Gnanapragasam, Priyanthi N P; Rzasa, Kara; Hatziioanno, Theodora; Durney, Michael A; Gu, Xiebin; Tada, Takuya; Landau, Nathaniel R; West, Anthony P; Rozenblatt-Rosen, Orit; Seaman, Michael S; Baden, Lindsey R; Graham, Daniel B; Deguine, Jacques; Bieniasz, Paul D; Regev, Aviv; Hung, Deborah; Bjorkman, Pamela J; Xavier, Ramnik J.

Cell ; 184(12): 3205-3221.e24, 2021 06 10.

Artigo Inglês | MEDLINE | ID: mdl-34015271

4.

Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques.

Alter, Galit; Yu, Wen-Han; Chandrashekar, Abishek; Borducchi, Erica N; Ghneim, Khader; Sharma, Ashish; Nedellec, Rebecca; McKenney, Katherine R; Linde, Caitlyn; Broge, Thomas; Suscovich, Todd J; Linnekin, Tom; Abbink, Peter; Mercado, Noe B; Nkolola, Joseph P; McMahan, Katherine; Bondzie, Esther A; Hamza, Venous; Peter, Lauren; Kordana, Nicole; Mahrokhian, Shant; Seaman, Michael S; Li, Wenjun; Lewis, Mark G; Lauffenburger, Douglas A; Hangartner, Lars; Sekaly, Rafick-Pierre; Barouch, Dan H.

Cell ; 183(1): 185-196.e14, 2020 10 01.

Artigo Inglês | MEDLINE | ID: mdl-33007262

5.

Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production.

Chen, Yuezhou; Zuiani, Adam; Fischinger, Stephanie; Mullur, Jyotsna; Atyeo, Caroline; Travers, Meghan; Lelis, Felipe J N; Pullen, Krista M; Martin, Hannah; Tong, Pei; Gautam, Avneesh; Habibi, Shaghayegh; Bensko, Jillian; Gakpo, Deborah; Feldman, Jared; Hauser, Blake M; Caradonna, Timothy M; Cai, Yongfei; Burke, John S; Lin, Junrui; Lederer, James A; Lam, Evan Christopher; Lavine, Christy L; Seaman, Michael S; Chen, Bing; Schmidt, Aaron G; Balazs, Alejandro Benjamin; Lauffenburger, Douglas A; Alter, Galit; Wesemann, Duane R.

Cell ; 183(6): 1496-1507.e16, 2020 12 10.

Artigo Inglês | MEDLINE | ID: mdl-33171099

6.

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.

Schommers, Philipp; Gruell, Henning; Abernathy, Morgan E; Tran, My-Kim; Dingens, Adam S; Gristick, Harry B; Barnes, Christopher O; Schoofs, Till; Schlotz, Maike; Vanshylla, Kanika; Kreer, Christoph; Weiland, Daniela; Holtick, Udo; Scheid, Christof; Valter, Markus M; van Gils, Marit J; Sanders, Rogier W; Vehreschild, Jörg J; Cornely, Oliver A; Lehmann, Clara; Fätkenheuer, Gerd; Seaman, Michael S; Bloom, Jesse D; Bjorkman, Pamela J; Klein, Florian.

Cell ; 180(3): 471-489.e22, 2020 02 06.

Artigo Inglês | MEDLINE | ID: mdl-32004464

7.

Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses.

Sajadi, Mohammad Mohseni; Dashti, Amir; Rikhtegaran Tehrani, Zahra; Tolbert, William D; Seaman, Michael S; Ouyang, Xin; Gohain, Neelakshi; Pazgier, Marzena; Kim, Dongkyoon; Cavet, Guy; Yared, Jean; Redfield, Robert R; Lewis, George K; DeVico, Anthony L.

Cell ; 173(7): 1783-1795.e14, 2018 06 14.

Artigo Inglês | MEDLINE | ID: mdl-29731169

8.

Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.

Horwitz, Joshua A; Bar-On, Yotam; Lu, Ching-Lan; Fera, Daniela; Lockhart, Ainsley A K; Lorenzi, Julio C C; Nogueira, Lilian; Golijanin, Jovana; Scheid, Johannes F; Seaman, Michael S; Gazumyan, Anna; Zolla-Pazner, Susan; Nussenzweig, Michel C.

Cell ; 170(4): 637-648.e10, 2017 Aug 10.

Artigo Inglês | MEDLINE | ID: mdl-28757252

9.

Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency.

Bournazos, Stylianos; Gazumyan, Anna; Seaman, Michael S; Nussenzweig, Michel C; Ravetch, Jeffrey V.

Cell ; 165(7): 1609-1620, 2016 Jun 16.

Artigo Inglês | MEDLINE | ID: mdl-27315478

10.

Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity.

Huang, Yaoxing; Yu, Jian; Lanzi, Anastasia; Yao, Xin; Andrews, Chasity D; Tsai, Lily; Gajjar, Mili R; Sun, Ming; Seaman, Michael S; Padte, Neal N; Ho, David D.

Cell ; 165(7): 1621-1631, 2016 Jun 16.

Artigo Inglês | MEDLINE | ID: mdl-27315479

11.

Intra-spike crosslinking overcomes antibody evasion by HIV-1.

Galimidi, Rachel P; Klein, Joshua S; Politzer, Maria S; Bai, Shiyu; Seaman, Michael S; Nussenzweig, Michel C; West, Anthony P; Bjorkman, Pamela J.

Cell ; 160(3): 433-46, 2015 Jan 29.

Artigo Inglês | MEDLINE | ID: mdl-25635457

12.

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.

Dosenovic, Pia; von Boehmer, Lotta; Escolano, Amelia; Jardine, Joseph; Freund, Natalia T; Gitlin, Alexander D; McGuire, Andrew T; Kulp, Daniel W; Oliveira, Thiago; Scharf, Louise; Pietzsch, John; Gray, Matthew D; Cupo, Albert; van Gils, Marit J; Yao, Kai-Hui; Liu, Cassie; Gazumyan, Anna; Seaman, Michael S; Björkman, Pamela J; Sanders, Rogier W; Moore, John P; Stamatatos, Leonidas; Schief, William R; Nussenzweig, Michel C.

Cell ; 161(7): 1505-15, 2015 Jun 18.

Artigo Inglês | MEDLINE | ID: mdl-26091035

13.

Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity.

Bournazos, Stylianos; Klein, Florian; Pietzsch, John; Seaman, Michael S; Nussenzweig, Michel C; Ravetch, Jeffrey V.

Cell ; 158(6): 1243-1253, 2014 Sep 11.

Artigo Inglês | MEDLINE | ID: mdl-25215485

14.

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice.

Halper-Stromberg, Ariel; Lu, Ching-Lan; Klein, Florian; Horwitz, Joshua A; Bournazos, Stylianos; Nogueira, Lilian; Eisenreich, Thomas R; Liu, Cassie; Gazumyan, Anna; Schaefer, Uwe; Furze, Rebecca C; Seaman, Michael S; Prinjha, Rab; Tarakhovsky, Alexander; Ravetch, Jeffrey V; Nussenzweig, Michel C.

Cell ; 158(5): 989-999, 2014 Aug 28.

Artigo Inglês | MEDLINE | ID: mdl-25131989

15.

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.

Schoofs, Till; Barnes, Christopher O; Suh-Toma, Nina; Golijanin, Jovana; Schommers, Philipp; Gruell, Henning; West, Anthony P; Bach, Franziska; Lee, Yu Erica; Nogueira, Lilian; Georgiev, Ivelin S; Bailer, Robert T; Czartoski, Julie; Mascola, John R; Seaman, Michael S; McElrath, M Juliana; Doria-Rose, Nicole A; Klein, Florian; Nussenzweig, Michel C; Bjorkman, Pamela J.

Immunity ; 50(6): 1513-1529.e9, 2019 06 18.

Artigo Inglês | MEDLINE | ID: mdl-31126879

16.

Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.

Klein, Florian; Diskin, Ron; Scheid, Johannes F; Gaebler, Christian; Mouquet, Hugo; Georgiev, Ivelin S; Pancera, Marie; Zhou, Tongqing; Incesu, Reha-Baris; Fu, Brooks Zhongzheng; Gnanapragasam, Priyanthi N P; Oliveira, Thiago Y; Seaman, Michael S; Kwong, Peter D; Bjorkman, Pamela J; Nussenzweig, Michel C.

Cell ; 153(1): 126-38, 2013 Mar 28.

Artigo Inglês | MEDLINE | ID: mdl-23540694

17.

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys.

Barouch, Dan H; Stephenson, Kathryn E; Borducchi, Erica N; Smith, Kaitlin; Stanley, Kelly; McNally, Anna G; Liu, Jinyan; Abbink, Peter; Maxfield, Lori F; Seaman, Michael S; Dugast, Anne-Sophie; Alter, Galit; Ferguson, Melissa; Li, Wenjun; Earl, Patricia L; Moss, Bernard; Giorgi, Elena E; Szinger, James J; Eller, Leigh Anne; Billings, Erik A; Rao, Mangala; Tovanabutra, Sodsai; Sanders-Buell, Eric; Weijtens, Mo; Pau, Maria G; Schuitemaker, Hanneke; Robb, Merlin L; Kim, Jerome H; Korber, Bette T; Michael, Nelson L.

Cell ; 155(3): 531-9, 2013 Oct 24.

Artigo Inglês | MEDLINE | ID: mdl-24243013

18.

Prolonged viral suppression with anti-HIV-1 antibody therapy.

Gaebler, Christian; Nogueira, Lilian; Stoffel, Elina; Oliveira, Thiago Y; Breton, Gaëlle; Millard, Katrina G; Turroja, Martina; Butler, Allison; Ramos, Victor; Seaman, Michael S; Reeves, Jacqueline D; Petroupoulos, Christos J; Shimeliovich, Irina; Gazumyan, Anna; Jiang, Caroline S; Jilg, Nikolaus; Scheid, Johannes F; Gandhi, Rajesh; Walker, Bruce D; Sneller, Michael C; Fauci, Anthony; Chun, Tae-Wook; Caskey, Marina; Nussenzweig, Michel C.

Nature ; 606(7913): 368-374, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-35418681

19.

Combination anti-HIV antibodies provide sustained virological suppression.

Sneller, Michael C; Blazkova, Jana; Justement, J Shawn; Shi, Victoria; Kennedy, Brooke D; Gittens, Kathleen; Tolstenko, Jekaterina; McCormack, Genevieve; Whitehead, Emily J; Schneck, Rachel F; Proschan, Michael A; Benko, Erika; Kovacs, Colin; Oguz, Cihan; Seaman, Michael S; Caskey, Marina; Nussenzweig, Michel C; Fauci, Anthony S; Moir, Susan; Chun, Tae-Wook.

Nature ; 606(7913): 375-381, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-35650437

20.

Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.

Fritschi, Christopher J; Anang, Saumya; Gong, Zhen; Mohammadi, Mohammadjavad; Richard, Jonathan; Bourassa, Catherine; Severino, Kenny T; Richter, Hannah; Yang, Derek; Chen, Hung-Ching; Chiu, Ta-Jung; Seaman, Michael S; Madani, Navid; Abrams, Cameron; Finzi, Andrés; Hendrickson, Wayne A; Sodroski, Joseph G; Smith, Amos B.

Proc Natl Acad Sci U S A ; 120(13): e2222073120, 2023 03 28.

Artigo Inglês | MEDLINE | ID: mdl-36961924

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